Nanoemulsions for “Nose-to-Brain” Drug Delivery
نویسندگان
چکیده
منابع مشابه
A Review on Nose-to-Brain Drug Delivery
Intranasal route of administration shows potential for delivery of drugs to brain. The nose-to-brain drug delivery of drugs is advantageous as it requires low dose of drug, avoids first pass effect. Also it is fast in action and suitable for the drugs that degrade in gastrointestinal tract. Nose-to-brain delivery also avoids blood brain barrier which is important factor to be considered in form...
متن کاملNose to Brain Drug Delivery: A Recent Update
Drugs used to treat brain or central nervous system disorder suffer from shortfall of absorption and reaching brain due to blood brain barrier and cerebro spinal fluid barrier. Intra nasal administration of brain targeted drug delivery system is gaining popularity to circumvent blood brain barrier and enhance drug availability in brain. It also shows promising reduction of systemic adverse effe...
متن کاملNose to Brain Drug Delivery: A Recent Update
Drugs used to treat brain or central nervous system disorder suffer from shortfall of absorption and reaching brain due to blood brain barrier and cerebro spinal fluid barrier. Intra nasal administration of brain targeted drug delivery system is gaining popularity to circumvent blood brain barrier and enhance drug availability in brain. It also shows promising reduction of systemic adverse effe...
متن کاملCurrent State of Nanoemulsions in Drug Delivery
Nanoemulsions have attracted great attention in research, dosage form design and pharmacotherapy. This is as a result of a number of attributes peculiar to nanoemulsions such as optical clarity, ease of preparation, thermodynamic stability and increased surface area. Nanoemulsions also known as submicron emulsions serve as vehicles for the delivery of active pharmaceutical ingredients as well a...
متن کاملProtein aerosol for intranasal nose to brain (N2B) delivery
Background For the treatment of metabolic and neurodegenerative diseases, drug delivery to the central nervous system (CNS) has gained considerable recent interest [1,2]. But many concepts for the delivery of therapeutic agents have failed by the natural blood-brain barrier (BBB). The N2B route for drugs is able to provide an adequate alternative of CNS drug delivery -bypassing the BBB [3,4]. N...
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ژورنال
عنوان ژورنال: Pharmaceutics
سال: 2019
ISSN: 1999-4923
DOI: 10.3390/pharmaceutics11020084